Thiagarajan Hemalatha » Публикация
Поделиться публикацией:
Опубликовано
2006-00-00
Опубликовано на SciPeople2011-06-14 06:22:23
ЖурналCryo Letters
Studies on biochemical markers in cryoinfarction in rats.
Аннотация
Cryoinfarction in rats was carried out by placing the cooled probe directly on the
midway of left anterior descending coronary artery. This caused damage to the blood vessel,
hindering blood flow to the distal part of the left ventricle. Gross pathology showed around
26 % infarction at 24 h. Histopathology revealed death of cardiomyocytes with blood vessel
congestion at the end of 24 h, inflammatory infiltrate at 48 h, fibrotic scar by 96 h and
collagen deposition by 192 h. Acute myocardial infarction biomarkers such as Cardiac
Troponin T, Creatine Kinase MB and NT pro BNP were shown to be elevated by 4 h. ECG
showed an ST segment elevation by 96 h. This cryoinfarction model was suitable to study
changes taking place during acute myocardial infarction in humans.
Комментарии
Вам необходимо зайти или зарегистрироваться для комментирования
Этот комментарий был удален
Этот комментарий был удален
Этот комментарий был удален