«Саратовский научно-медицинский журнал» » Архив номеров » Volume 7, issue 1 » Публикация

Аннотация The aim of investigation is to study heart hemodynamics in teenagers with connective tissue dysplasia of heart (CTDH). 35 patients ages 12 to 15 years with CTDH have been observed: Group I (n=14) are the patients with mitral valve prolapse (MVP) without mitral regurgitation (MR) and myxomatous degeneration(MD) or isolated minor heart abnormalities (MHA), Group II (n=11)are patients with MVP and MR in combination with 1 or2 MHA, and Group III (n=10) are patients with MVP and mixoid degeneration (MD) in combination with 2 or more MHA. The control group consisted of 15 patients of the same age without MHA. All the children passed Doppler and echocardiography. According to the results significant changes of cardiohemodynamic indices in patients of Group I were not observed. The changes of size and volume indices of the left ventricle (LV), increase in wall thickness and diastolic dysfunction of the LV were observed in Group II. The significant changes of systolic function of left ventricular myocardium were observed in Group III. The study comes to the conclusion that teenagers with CTDH have definite changes of heart hemodynamics and functional state of left ventricular myocardium. These changes depend on mitral regurgitation, myxomatous degeneration and MHA combination