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Опубликовано 2011-12-25 Опубликовано на SciPeople2012-04-23 14:40:06 ЖурналSaratov Journal of Medical Scientific Research


Level of circulating cytokines and microelements in patients with hemorrhagic fever accompanied by renal syndrome
Khasanova G.M. Level of circulating cytokines and microelements in patients with hemorrhagic fever accompanied by renal syndrome // Saratov Journal of Medical Scientific Research, Vol. 7, Issue 4, 2011, pp. 863-865
Аннотация The research goal is to examine the interrelation of cytokines level (INF-y, TNF-a, IL-2, IL-4, IL-10) and concentration of microelements in blood of patients with hemorrhagic fever accompanied by renal syndrome. 292 patients aged 18-59 years have been examined.Enzyme immunodetection has been carried out by using reagents from «Vector-Best» (Novosibirsk). The content of microelements in blood plasma has been estimated by mass spectrometry with inductively coupled plasma (ICP-MS; Elan-9000, PerkinElmer, USA) and atomic emission spectrometry with inductively coupled plasma (ICP-OES; Optima-2000 DV, PerkinElmer, USA). A direct correlation between zinc, selenium, the level of IL-2 and lead, aluminum, the level of TNF-a has been found out. The negative correlation between aluminum concentration and the level of IF-y has been determined
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