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Опубликовано 2012-00-00 Опубликовано на SciPeople2012-07-30 16:22:19 ЖурналApplied Microbiology and Biotechnology

Microbial transformation of azaarenes and potential uses in pharmaceutical synthesis

Igor A. Parshikov, Alexander I. Netrusov and John B. Sutherland / Игорь Паршиков

Applied Microbiology and Biotechnology. 2012. V.95. N 4. P.871-889, DOI: 10.1007/s00253-012-4220-z

Аннотация Pyridine, quinoline, acridine, indole, carbazole, and other heterocyclic nitrogen-containing compounds (azaarenes) can be transformed by cultures of bacteria and fungi to produce a variety of new derivatives, many of which have biological activity. In many cases, the microbial biotransformation processes are regio- and stereoselective so that the transformation products may be useful for the synthesis of new candidate drugs.