«Саратовский научно-медицинский журнал» » Архив номеров » Volume 8, issue 2 » Публикация
Опубликовано
2012-06-25
Опубликовано на SciPeople2012-12-05 15:29:51
ЖурналSaratov Journal of Medical Scientific Research
Index of early renal damage in children with vesicoureteral reflux
Lakomova D.Yu. Index of early renal damage in children with vesicoureteral reflux // Saratov Journal of Medical Scientific Research, Vol. 8, Issue 2, 2012, pp. 318-324
Аннотация
Objective: To determine sensitive and objective criteria of nephrosclerosis by testing the levels of markers of inflammation (MCP-1), fibrogenesis (TGF-(31), renal parenchymal damage (collagen type IV, a-GST, тт-GST), angiogenesis (VEGF) in urine of children with vesicoureteral reflux (VUR). Materials and methods: 80 patients with different stages of VUR have been observed before and 6 months after treatment. Results: «Index of early renal damage» can be found as correlation between VEGF and collagen type IV concentration. Conclusion: Estimation of «index of early renal damage» could be included in pediatric practice for the control of urinary tract dysfunction in children with VUR
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