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Опубликовано 1999-05-21 Опубликовано на SciPeople2013-01-23 12:27:36 ЖурналApplied Microbiology and Biotechnology

Biotransformation of N-acetylphenothiazine by fungi

Parshikov I. A., Freeman J. P., Williams A. J., Moody J. D., Sutherland J. B. / Игорь Паршиков

Appl. Microbiol. Biotechnol. 1999. V. 52. P.553-557.

Аннотация Cultures of the fungi Aspergillus niger, Cunninghamella verticillata, and Penicillium simplicissimum, grown in a sucrose/peptone medium, transformed N-acetylphenothiazine to N-acetylphenothiazine sulfoxide (from 13% to 28% of the total) and phenothiazine sulfoxide (from 5% to 27%). Phenothiazin-3-one (4%) and phenothiazine N-glucoside (4%) were also produced by C. verticillata. The probable intermediate, phenothiazine, was detected only in cultures of P. simplicissimum (6%)