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Аннотация MONITORING OF ANTHROPOTOXINS IN ATMOSPHERE OF ARTIFICIAL OBJECTS Stolyarov S.B., Zamana S.P., Vershinin V.V., Nilipovskiy V.I., Fedorovskiy T.G., Sokolov S.A. The State University of Land Use Planning, Moscow, Russia, Stolyarov B. S., Korneyeva Е.А. Mephi, Moscow, Russia Presence of а human in Artificial Atmospheres of Hermetically Sealed Chambers (AAHSC) pollutes the atmosphere among other agents with endotoxins, therefore one of the key points in optimization AAHSC is sanitation and contamination estimate of the proportion of the agents in AAHSC. This estimate should be aimed at specification of safe concentration of harmful agents. AAHSC is polluted with human metabolites: carbon monoxide, phenols, ammonia, acetone, dimethylamine and methane. Resulting from experimental works for the Maximum Allowable Concentrations have been developed in mg/m3 as follows: ammonia – 5, aliphatic hydrocarbons – 300, amino compounds-1, acetone - 50, СО – 15, phenols - 0,3. In 6 days residence time the exhaled air in AAHSC contains 4 times higher level of acetone, 1,4 times – of carbon monoxide (CO). Excretion of hexane and ethanol after initial fall-off almost doubles in 10 day’s time. However, by the 15th day hexane concentration recovers its original value, while ethanol keeps increased value. Acetaldehyde concentration of 0,1 mg/m3 in the exhaled air increases to 0,15 mg/m3 not until the 5th day. From toxicological point of vier, such metabolites as CO and CO2 are of the greatest importance. Estimation of the combined effect of both has shown that given low concentration one can observe separate effects, given high - strengthening of toxic effect. One of the waste products, forming AAHSC, is methane. Literary data on the quantity of methane emitted by a human differ. The researchers examined 300 men of about 20 years old before putting the examinees into exactly the same extreme conditions and after. This experiments showed that methane level in exhaled air of different people varied from 0,1 to 30 mg/m3. Average value equals to 2,8±0,7 mg/m3. However extensive population variability of methane levels in the exhaled air was, a gas chromatograph proved able to respond to inter-temporal changes of methane concentration of each individual. Therefore, these changes altogether with supplementary data may describe individual peculiarities of human metabolic processes. Multidirected change of enzymic strength of neutrophils and feeling unwell arises from exposure to CO, oxides of nitrogen, and hydrocarbons levelled 5-110, 0,1-15, 60-130 mg/m3 respectively. The received data, having shown that toxic pollutants cause distinct changes of cytochemical indices, can become informative criterion to estimate effects produced by anthropotoxins. The data given proves that the level of metabolites in exhaled air indicates fitness of a person fairly just, because it reflects complex alterations of metabolic processes in extreme conditions. The connections that have been found allow us to take the part of exhaled air in forming AAHSC with much consideration. Dynamics of cumulation of anthropotoxins makes it impossible for a man to stay in AAHSC long without their being disposed of.