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Опубликовано 2014-03-12 Опубликовано на SciPeople2014-03-12 19:25:33 ЖурналChemistry of Heterocyclic Compounds

Microbial transformations of piperideine and pyridine derivatives

Modyanova L.V., Duduchava M.R., Piskunkova N.F., Grishina G.V., Terentyev P.B., Parshikov I.A. / Игорь Паршиков

Chemistry of Heterocyclic Compounds, 1999, v. 33, N5, P. 580-586

Аннотация Optically active 2-(4-hydroxyphenylcarbamoyloxymethyl)-1-methyl-1,2,5,6-tetrahydropyridine is obtained on microbiological transformation of 1-methyl-2-(N-phenyl-carbamoyloxymethyl)-1,2,5,6-tetrahydropyridine with a growing culture of the fungus C. verticillata VKPM F-430. Transformation of 2-(2-phenylethyl)pyridine by a methanoxidating culture of Methylococcus occurs either by hydroxylation of the side chain or conversion of the substrate into N-oxide, depending on the process conditions.