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Опубликовано 2014-09-25 Опубликовано на SciPeople2015-02-18 01:08:40 ЖурналSaratov Journal of Medical Scientific Research

Cytokines balance change in gingival fluid at periodontal diseases and its value for the prognosis of regeneration disturbances in periodontal tissues

Ostrovskaya L.Yu., Zakharova N.B., Mogila А.Р., Katkhanova L.S., Akulova E.V., Popykhova E.B. / Антон Киселев ^{контактное лицо}

Ostrovskaya L.Yu., Zakharova N.B., Mogila А.Р., Katkhanova L.S., Akulova E.V., Popykhova E.B. Cytokines balance change in gingival fluid at periodontal diseases and its value for the prognosis of regeneration disturbances in periodontal tissues // Saratov Journal of Medical Scientific Research, Vol. 10, Issue 3, 2014, pp. 435-440

Аннотация Purpose: To establish diagnostic value of the increased content of pro- and anti-inflammatory cytokines (IL-8, MCP-1, RAIL) in gingival fluid at patients with a chronic periodontal disease. Material and Methods: 60 patients with inflammatory periodontal diseases were surveyed. The concentration of the studied cytokines in gingival fluid has been defined. Results: At a periodontal disease the increased level of pro- and anti-inflammatory cytokines in gingival fluid has been noted. Conclusion: Definition of the MCP-1 and IL-8 levels in gingival fluid can be used as a criterion of the prognosis of the severity of inflammatory and destructive processes in the periodontal tissues.