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Опубликовано 2015-03-25 Опубликовано на SciPeople2015-08-07 21:13:26 ЖурналSaratov Journal of Medical Scientific Research

Heart ischemic disease and longevity: unsolved problems
Markova T.Yu., Malinova L.I., Denisova Т.Р. / Антон Киселев контактное лицо
Markova T.Yu., Malinova L.I., Denisova Т.Р. Heart ischemic disease and longevity: unsolved problems // Saratov Journal of Medical Scientific Research, Vol. 11, Issue 1, 2015, pp. 37-41
Аннотация The purpose of the study was to estimate clinical signs and course of coronary heart disease in long-livers and centenarians. Material and Methods. The study included overall population of Saratov — Engels agglomeration's long-livers (>=90 years old, n=198). Results. The rates of major clinical forms of coronary heart disease were detected: atrial fibrillation — 10.6%, chronic heart failure (with preserved ejection fraction) — 10.1 % and angina — 5.1 %. Myocardial infarction was verified in 9.6% of long-livers. Myocardial scar criteria prevailed over myocardial infarction history. Received data corroborated dissolving phenomena of coronary heart disease and noninsulin dependent diabetes mellitus in long-livers. Gender differences in electrophysiological parameters were detected in long-livers. Centenarians with the history of myocardial infarction preserved a satisfactory level of physical activity. Conclusion. Received data confirm a presence of an excessive security: prevention of coronary heart disease manifestation and progression in longevity. Long-livers should be considered as a natural model of an antiatherogenic factors and mechanisms.
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