«Саратовский научно-медицинский журнал» » Архив номеров » Volume 6, issue 1 » Публикация

Поделиться публикацией:
Опубликовать в блог:
Опубликовано 2010-03-25 Опубликовано на SciPeople2010-04-20 23:31:26 ЖурналSaratov Journal of Medical Scientific Research


State of renal hemodynamics and nephrofibrosis parameters in patients with nephrolithiasis applying angiotensin converting enzyme inhibitors
P.V. Glybochko, A.A. Svistunov, A.N. Rossolovsky, O.L. Berezinetz, N.B. Zakharova, A.P. Abramova / Антон Киселев контактное лицо
P.V. Glybochko, A.A. Svistunov, A.N. Rossolovsky, O.L. Berezinetz, N.B. Zakharova, A.P. Abramova State of renal hemodynamics and nephrofibrosis parameters in patients with nephrolithiasis applying angiotensin converting enzyme inhibitors // Saratov Journal of Medical Scientific Research, Vol. 6, Issue 1, 2010, pp. 170-173
Аннотация The aim of the study is to evaluate the influence of angiotensin converting enzyme (ACE) inhibitors of quinapril on the condition of renal hemodynamics, changes of profibrotic cytokines level and transforming growth factor at patients with nephrolithiasis undergone various kinds of surgery. Patients were divided into 2 groups initially and in 1 month after surgery. Concentrations of IL-6, TGFp and МСР-1 were determined in blood serum. Assessment of renal blood flow state by Doppler ultrasonography was performed in the same terms. As a result of quinapril treatment the decrease of МСР-1, TGFp and IL-6 was marked in comparison with the group which did not receive nephroprotective therapy. The analysis of Doppler ultrasonography data showed authentic improvement of renal blood flow in 1 month after surgery. The most informative parameter proved to be the resistance index that indicated the decrease of vascular resistance after surgical treatment in condition of quinapril therapy
Ключевые слова публикации:
       

Комментарии

Вам необходимо зайти или зарегистрироваться для комментирования
Этот комментарий был удален
Этот комментарий был удален