PhD Positions in Neuroimmunolgy; Institute for Multiple Sclerosis Research, Dept. of Neuroimmunology, University of Goettingen, Germany
The Institute for Multiple Sclerosis Research, Dept. of Neuroimmunology of the Georg-August University Goettingen is looking for PhD students interested in neuroimmunology.
The group is focused on autoimmune disease processes of the nervous system. Modern optical (intravital 2-photon microcopy) and molecular techniques are employed to study the role of immune cells in the disease pathogenesis of experimental autoimmune encephalomyelitis, a disease model for multiple sclerosis. We offer optimal working conditions in an excellent scientific environment, which includes different Neuroscience PhD programs organized by the University of Goettingen and the Max Planck Institutes for Experimental Medicine and Biophysical Chemistry. We are looking for graduates with a background in immunology, neurobiology or imaging technologies who are strongly committed to and enthusiastic about science and research.
Please visit our homepage for an overview of current projects: http://www.neuroimmunologie.uni-goettingen.de
We are looking forward to your application.
Please send your application and CV, preferably electronically to:
Professor Alexander Flügel
imsf[ at ]med.uni-goettingen.de
Institute for Multiple Sclerosis Research / Dept. of Neuroimmunology
Waldweg 33
37073 Goettingen
Germany
Ph.: +49 (0)551 39 13332
Fax: +49 (0)551 39 13348
Selected References:
C. Cordiglieri, F. Odoardi, B. Zhang, M. Nebel, N. Kawakami, W.E.F. Klinkert, D. Lodygin, F. Lühder, E. Breunig, D. Schild, V. Kumar, K. Dornmair, W. Dammermann; B.V.L. Potter, A.H. Guse, A. Flügel. NAADP-mediated Ca2+ signaling in effector T cells regulates autoimmunity of the nervous system, Brain 133 (2010): 1930-43.
I. Bartholomäus, N. Kawakami, F. Odoardi, C. Schläger, D. Miljkovic, J.W. Ellwart, W.E. Klinkert, T.B. Issekutz, C. Flügel-Koch, H. Wekerle, A. Flügel. The groping lymphocyte: Tactile interactions of incoming effector T cells with blood brain barrier-associated structures in nascent autoimmune CNS lesions, Nature 462 (2009):94-8.
F. Odoardi, N. Kawakami, W.E.F. Klinkert, H. Wekerle, A. Flügel. Blood-born soluble protein antigen intensifies T cell activation in autoimmune CNS lesions and exacerbates clinical disease. Proceedings of the National Academy of Sciences of the United States of America 104 (2007): 18625-18630.
Kawakami N, Nägerl UV, Odoardi F, Bonhoeffer T, Wekerle H, Flügel A. Live imaging of effector cell trafficking and autoantigen recognition within the unfolding autoimmune encephalomyelitis lesion. J Exp Med. 2005 Jun 6;201(11):1805-14.
F. Lühder, Y. Huang, K.M. Dennehy, C. Guntermann , I. Müller, E. Winkler, T. Kerkau, S. Ikemizu, S.J. Davis, T. Hanke, T. Hünig. (2003) Topological requirements and signaling properties of T cell-activating, anti-CD28 antibody superagonists. J Exp Med. 197, 955-66.
Link:
PhD Positions in Neuroimmunolgy; Institute for Multiple Sclerosis Research, Dept. of Neuroimmunology, University of Goettingen, Germany
The Institute for Multiple Sclerosis Research, Dept. of Neuroimmunology of the Georg-August University Goettingen is looking for PhD students interested in neuroimmunology.
The group is focused on autoimmune disease processes of the nervous system. Modern optical (intravital 2-photon microcopy) and molecular techniques are employed to study the role of immune cells in the disease pathogenesis of experimental autoimmune encephalomyelitis, a disease model for multiple sclerosis. We offer optimal working conditions in an excellent scientific environment, which includes different Neuroscience PhD programs organized by the University of Goettingen and the Max Planck Institutes for Experimental Medicine and Biophysical Chemistry. We are looking for graduates with a background in immunology, neurobiology or imaging technologies who are strongly committed to and enthusiastic about science and research.
Please visit our homepage for an overview of current projects: http://www.neuroimmunologie.uni-goettingen.de<
Country: Germany
