We determined the cytotoxic effect of iron nanoparticles of 70 nm, with a single per oral administration in an experiment on white outbred mice. Morphological changes were evaluated in the internal organs.
Thus, changes depend on the concentration of nanoparticles at long-term per oral exposure: identified violations of the structure of the liver, kidneys and spleen as venous plethora and degeneration of cells at 250 and 500 mkg / kg dose of nanoparticles are reversible, changes in the organs were pronounced with a dosage of 1000 mkg / kg.
Публикация
N A Navolokin et al 2012 J. Phys.: Conf. Ser. 345 012043 doi:10.1088/1742-6596/345/1/012043
Статистика
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