Russian Open Medical Journal » Архив номеров » Volume 2, issue 3 » Публикация

Аннотация The rate of anthropogenic pollution and reduction of the environmental quality progress quicker than adaptive possibilities of an organism. This causes pre-pathological and pathological changes. So there is a necessity of preventive measures organization to eliminate toxic load and accelerated eliminating of xenobiotics from an organism. The discoveries of the recent 15 years had been revealed the possibility to change complexons (which are used for detoxication) to dietary fibers, pectin as well. Meanwhile pectin substances are not widely used in clinical practice, and their efficiency comparing with small concentrations of cumulating poisons had not been studied yet. During the development of the detoxification nutritional therapy at patients with different pathology of the digestive system organs (with the revealed heavy metals and organochlorine pesticides) there had been organized tests of pectin efficiency (citrus and apple) for reducing the contamination with these xenobiotics. After the course of pectin treatment there had been fixed not only the reduce of toxic heavy metals, but essential microelements as well, which is connected with nonselective complexing capability of pectin substances. The probe tests also showed that course of citrus pectin treatment favored total excretion of organochlorine pesticides at 11.0% of patients, at other patients pesticide level reduced up to minimal rate (revealed by gas chromatographic method 0.0001 mg/dm³). There is a significant difference of values before and after pectin treatment. At the same time at patients who had not taken enterosorbent (compare group) the level of organochlorine pesticides after repeated tests stayed on the level close to the basic. There had been discussed mechanism of excretion of organochlorine pesticides and heavy metals with the help of pectins.