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Научные и исследовательские проекты

Control of Gene Expression: molecular mechanisms that regulate RNA polymerase I transcription initiation and elongation.

Synthesis of ribosomes is a sophisticated and tightly controlled process in all living cells. Transcription of ribosomal RNA (rRNA) by RNA polymerase I can account for more than 60% of the total transcription in a growing cell. The molecular mechanisms that control the synthesis of rRNA are the focus of our research group. The research in Dr. Schneider's lab addresses three general...